TIDAL: Target-Induced Droplet Assembly of Ligands
Special Notice monitored from sam-gov.
- Buyer / agency
- ENERGY, DEPARTMENT OF
- Notice type
- Special Notice
- Solicitation number
- S-197478
- Posted
- September 8, 2026
- Response deadline
- December 9, 2026
- Location
- NM, US
- Estimated value
- Not published by the source
- NAICS
- 541714
- Source
- sam-gov
Summary
Developed by Los Alamos National Laboratory, TIDAL (Target-Induced Droplet Assembly of Ligands) transforms the small antibody fragments known as nanobodies into a programmable, protein-only material that organizes itself on demand. By harnessing a natural process called liquid-liquid phase separation, TIDAL lets these binders gather into dense, dynamic droplets precisely when they encounter their intended target, giving developers a single platform that can purify proteins wi…
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